Are leukocytes labeled with stabilized 99mTc-HMPAO becoming activated during labeling?
نویسندگان
چکیده
منابع مشابه
Preparation and labeling of HMPAO kit in Iran [Persian]
In recent years, several radiopharmaceuticals have been developed for imaging regional cerebral blood flow (rCBF) such as 75Se labelled PIPSE and MOSE, ²º¹TI labelled DDC and 99mTc labelled HMPAO. HMPAO with two asymmetric carbon atoms (At the 3 and 9 positions), produces d,1 and meso isomers, only one of which is retained in the brain. Rapid intracellular conversion of 99mTc-d,1-HMPAO to...
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متن کاملHMPAO Becoming Activated During Labeling?
TO THE EDITOR: We read with interest the recent article by Robins et al. (1) in which they reported biokinetic data of leukocytes labeled with stabilized 99mTc-HMPAO (exametazime) by a method that had earlier been described by their group in this journal (2) and elsewhere (3), with minor differences in methodology and results. Labeling white cells with technetium rather than indium has obvious ...
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The in vitro viability, chemotaxis, and labeling stability of leukocytes labeled using 99mTc-exametazime stabilized with methylene blue were evaluated and compared with those obtained using nonstabilized 99mTc-exametazime. Methods: Two identical leukocyte populations, from 30 healthy donors, were labeled simultaneously using freshly prepared and 2-h-old stabilized 99mTc-exametazime. The followi...
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ورودعنوان ژورنال:
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine
دوره 42 4 شماره
صفحات -
تاریخ انتشار 2001